The increasing complexity of regulatory updates from global authorities presents significant challenges for medical device manufacturers, necessitating agile strategies to sustain compliance and maintain market access. Concurrently, regulatory bodies must effectively monitor manufacturers' responses and develop strategic surveillance plans. This study employs a multi-agent modeling approach, enhanced with Large Language Models (LLMs), to simulate regulatory dynamics and examine the adaptive behaviors of key actors, including regulatory bodies, manufacturers, and competitors. These agents operate within a simulated environment governed by regulatory flow theory, capturing the impacts of regulatory changes on compliance decisions, market adaptation, and innovation strategies. Our findings illuminate the influence of regulatory shifts on industry behaviour and identify strategic opportunities for improving regulatory practices, optimizing compliance, and fostering innovation. By leveraging the integration of multi-agent systems and LLMs, this research provides a novel perspective and offers actionable insights for stakeholders navigating the evolving regulatory landscape of the medical device industry.

We study the problem of recommending relevant products to users in relatively resource-scarce markets by leveraging data from similar, richer in resource auxiliary markets. We hypothesize that data from one market can be used to improve performance in another. Only a few studies have been conducted in this area, partly due to the lack of publicly available experimental data. To this end, we collect and release XMarket, a large dataset covering 18 local markets on 16 different product categories, featuring 52.5 million user-item interactions. We introduce and formalize the problem of cross-market product recommendation, i.e., market adaptation.